Juvenile xanthogranuloma
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Emiphumeleni ka-2022 ye-Stiftung Warentest evela eJalimane, ukwaneliseka kwabathengi nge-ModelDerm bekungaphansi kancane kunokuxhumana okukhokhelwayo kwe-telemedicine.
Emiphumeleni ka-2022 ye-Stiftung Warentest evela eJalimane, ukwaneliseka kwabathengi nge-ModelDerm bekungaphansi kancane kunokuxhumana okukhokhelwayo kwe-telemedicine.
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ReferencesI-Juvenile xanthogranuloma (JXG) iyisimo esivame kakhulu futhi uhlobo oluvame kakhulu lwe‑non‑Langerhans cell histiocytic disorder ezinganeni. Ezimweni ezifika ku‑75 %, lezi zilonda zivela ngonyaka wokuqala wokuphila, futhi ngaphezu kuka‑15‑20 % wabantu abathintekayo bazithola kusukela bazalwa. Nakuba ingavamile kubantu abadala, i‑JXG ivamise ukuvela kubantu abaneminyaka engama‑20 kuya kwama‑30, futhi iziguli eziningi ezindala ziba nesilonda esisodwa kuphela. Ngokomtholampilo, kubonakala njengamaqhwa noma izigaxa eziqinile eziphuzi noma ezinsundu, ikakhulukazi ebusweni, entanyeni, nasemathanjeni. Izilonda zomlomo azivamile kodwa zingase zibonakale njengesigaxa esiphuzi emaceleni olimi noma kwenye indawo emlonyeni, okungenzeka kubangele ukuvuvukala nokopha. Izilonda zesikhumba ngokuvamile azibangeli izimpawu futhi zivame ukuhamba ngokwazo eminyakeni embalwa. Nakuba kungavamile, ukubandakanyeka kwamehlo kuyinto evamile kakhulu ngaphandle kwesikhumba, okulandelwa ukubandakanyeka kwamaphaphu. I‑Ocular JXG ngokuvamile ithinta iso elilodwa kuphela futhi kwenzeka ngaphansi kuka‑0.5 % wabantu abathintekayo, nakuba cishe u‑40 % walabo abanezinkinga zamehlo babe nezilonda eziningi esikhumbeni lapho bexilongwa.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) azivamile, futhi ziyizifo eziyingozi ezihlangene nesigaba esikhulu se-non-Langerhans cell histiocytoses. Ngokuvamile, zivela njengamajele amancane noma amaningi anombala obomvu noma ophuzi, avame ukutholakala ekhanda noma entanyeni. Ama-JXG amaningi avame ukuvela ngesikhathi sokuzalwa noma phakathi nonyaka wokuqala wokuphila. Nakuba kungavamile, ngezinye izikhathi zingathinta izindawo ezingaphandle kwesikhumba; ukubandakanyeka kwamehlo kuyinto okufanele ibhekwe ngokusho kwezincwadi ezikhona. Ngokuvamile, ama-JXG esikhumba ayazihambela futhi awadingi ukwelashwa.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Izilonda ze‑ocular zibonakala ku‑10 % wabantu abane‑JXG futhi zingathinta ukubona kwabo. Nakuba izilonda zesikhumba ngokuvamile ziyanyamalala ngokwemvelo, izilonda zamehlo azivamile ukuvela futhi zidinga ukwelashwa.